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HSP77/76 Polyclonal Antibody, 100ul Serological Pipets Ser-376 and Ser-212 are autophosphorylated

SKU: 82109408916

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HSP77/76 Polyclonal Antibody, 100ul Serological Pipets Ser-376 and Ser-212 are autophosphorylatedCould be the product of a pseudogene.,In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by

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Description

Ser-376 and Ser-212 are autophosphorylated by the C-terminal kinase domain

Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH)

IRF7 and ISG15

This gene is deleted in Williams-Beuren syndrome

The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs)| which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia

HSP77/76 Polyclonal Antibody, 100ul Serological Pipets Ser-376 and Ser-212 are autophosphorylatedCould be the product of a pseudogene.,In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by

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