SNPH Polyclonal Antibody, 50ul Peptide Synthesis MAPKK kinase/MEKK phosphorylates and activates

MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase

Acts as a negative mediator of apoptosis and may play a role in tumor progression

Certain mutations in this gene cause butterfly-shaped pigment dystrophy

A related pseudogene has been identified on chromosome 9

SUBCELLULAR LOCATION: cell membrane

SNPH Polyclonal Antibody, 50ul Peptide Synthesis MAPKK kinase/MEKK phosphorylates and activatesSyntaxin 1, synaptobrevin VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane associated and inhibits SNARE complex formation by binding free syntaxin 1. Expression of this gene appears to be brain specific. Alternative splicing results in multiple transcript variants encoding different isoforms.