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GTR2 Polyclonal Antibody, 50ul Molecular Biologyn Recruits TRAF3 and DISC1 to

SKU: 81597540016

4.1
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GTR2 Polyclonal Antibody, 50ul Molecular Biologyn Recruits TRAF3 and DISC1 toThis gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi Bickel syndrome and noninsulin dependent diabetes mellitus (NIDDM). Alternative

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Description

Recruits TRAF3 and DISC1 to the microtubules

This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined

Alternatively spliced transcript variants encoding different isoforms have been identified for CAV2

Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA)

Contains 2 LRR (leucine-rich) repeats

GTR2 Polyclonal Antibody, 50ul Molecular Biologyn Recruits TRAF3 and DISC1 toThis gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi Bickel syndrome and noninsulin dependent diabetes mellitus (NIDDM). Alternative

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