Rat Collectrin, TMEM27 ELISA Kit, 96T Serum & Sample Tubes Alternative splicing results in multiple

Alternative splicing results in multiple transcript variants encoding the same protein

The cytogenetic location of this locus has been reported as both 8p11 and 8q11

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes

Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric

Expression of MEKK4 in mammalian cells activated the CSBP2 and JNK MAPK pathways

Rat Collectrin, TMEM27 ELISA Kit, 96T Serum & Sample Tubes Alternative splicing results in multiplePlays an important role in amino acid transport by acting as binding partner of amino acid transporters SLC6A18 and SLC6A19, regulating their trafficking on the cell surface and their activity (By similarity). May also play a role in trafficking of amino acid transporters SLC3A1 and SLC7A9 to the renal cortical cell membrane (By similarity). Regulator of SNARE complex function (PubMed: 16330323). Stimulator of beta cell replication (By similarity).