Crk II(Phospho Tyr221) Polyclonal Antibody, 20ul Mini dry bath The MUTYH gene is located

The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis

FAM90A20 belongs to subfamily II of the primate-specific FAM90A gene family| which originated from multiple duplications and rearrangements (Bosch et al

CRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion

Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction

the SH2 domain targets SH2 domain-containing proteins to tyrosine-phosphorylated sites

Crk II(Phospho Tyr221) Polyclonal Antibody, 20ul Mini dry bath The MUTYH gene is locatedThis gene encodes a member of an adapter protein family that binds to several tyrosine phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2 phosphotyrosine interaction. The N terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C