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NTCP2 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation TAS2R44 belongs to the large

SKU: 80668989068

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NTCP2 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation TAS2R44 belongs to the largeThis gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines

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Description

TAS2R44 belongs to the large TAS2R receptor family

Sequence analysis identified multiple transcript variants encodin

Family members play essential roles in innate immune response to a wide range of pathogenic organisms| tissue damage and other cellular stresses

The encoded protein carries the John Milton Hagen (JMH) blood group antigens

H3F3A contains introns and its mRNA is polyadenylated

NTCP2 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation TAS2R44 belongs to the largeThis gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines

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