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PDE3A Polyclonal Antibody, 50ul Immunoassays The expression of the CA3

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PDE3A Polyclonal Antibody, 50ul Immunoassays The expression of the CA3This gene encodes a member of the cGMP inhibited cyclic nucleotide phosphodiesterase (cGI PDE) family. cGI PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and

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Description

The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle

It has been also shown to play an important role in the proliferation and differentiation of B cells

Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons

The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases

proteins interact with protein kinases and may serve as targets for activated GTPase

PDE3A Polyclonal Antibody, 50ul Immunoassays The expression of the CA3This gene encodes a member of the cGMP inhibited cyclic nucleotide phosphodiesterase (cGI PDE) family. cGI PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and

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