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SDHA Polyclonal Antibody, 50ul Funnels At the nucleoplasmic side of

SKU: 80283153153

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SDHA Polyclonal Antibody, 50ul Funnels At the nucleoplasmic side ofSDHA encodes a major catalytic subunit of succinate ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript

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Description

At the nucleoplasmic side of the NPC

It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation

which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls

The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins

This gene is a candidate gene for cleft palate

SDHA Polyclonal Antibody, 50ul Funnels At the nucleoplasmic side ofSDHA encodes a major catalytic subunit of succinate ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript

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