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Pax-6 Monoclonal Antibody, 50ul Aspirating Pipets SP100 (SP100 nuclear antigen) encodes

SKU: 79884247838

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Pax-6 Monoclonal Antibody, 50ul Aspirating Pipets SP100 (SP100 nuclear antigen) encodesThis gene encodes a homeobox and paired domain containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of

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Description

SP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies

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where it phosphorylates and inactivates BCKD

May be concerned with increased secretion of cytokines associated with cellular senescence

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Pax-6 Monoclonal Antibody, 50ul Aspirating Pipets SP100 (SP100 nuclear antigen) encodesThis gene encodes a homeobox and paired domain containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of

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