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ERK 1 Polyclonal Antibody, 100ul Cell Culture Flasks A translocation involving this gene

SKU: 79753247702

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ERK 1 Polyclonal Antibody, 100ul Cell Culture Flasks A translocation involving this geneMitogen activated protein kinase 3 encoded by MAPK3 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it

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Description

A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene| encoding a DNA binding protein| located on chromosome 11 is associated with leukemia

Allelic variations in this gene have been associated| but not causally linked| with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS)

Single nucleotide polymorphisms in this gene are associated with Kawasaki disease

Contains 5 C2 domains

It may have additional roles in enhancing sperm motility

ERK 1 Polyclonal Antibody, 100ul Cell Culture Flasks A translocation involving this geneMitogen activated protein kinase 3 encoded by MAPK3 is a member of the MAP kinase family. MAP kinases, also known as extracellular signal regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it

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