NFKappaB-p100 Polyclonal Antibody, 100ul[BT-AP05973] Sealing Film Known functions for this protein

Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases

Ras-related protein Rap-2c has been reported to activate in vitro transcriptional activity of the serum response element

Although the encoded protein is a member of the peptidase S1 family of serine proteases

and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism

Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes

NFKappaB-p100 Polyclonal Antibody, 100ul[BT-AP05973] Sealing Film Known functions for this proteinNFKB2 encodes a subunit of the transcription factor complex nuclear factor kappa B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. Nuclear factor kappa B subunit 2 encoded by NFKB2 can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full length protein is co translationally processed into a