PDE1A Polyclonal Antibody, 100ul Isothermal Amplification Contains 27 ANK repeats

Contains 27 ANK repeats

The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130

The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor

subunit:Interacts (via SH3 domain) with COL7A1

Among its related pathways are Glycine

PDE1A Polyclonal Antibody, 100ul Isothermal Amplification Contains 27 ANK repeatsCyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and or cGMP to their respective nucleoside 5 prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+) calmodulin (see CALM1; MIM 114180) dependent PDEs (CaM PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001