JAK1 Polyclonal Antibody, 100ul[BT-AP04683] Enzyme-Linked Immunosorbent Assay (ELISA) Three of the transcript variants

Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons

The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis

DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus

G-protein-coupled (EDG) receptor gene family

Multiple transcript variants encoding different isoenzymes have been identified for this gene| some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates

JAK1 Polyclonal Antibody, 100ul[BT-AP04683] Enzyme-Linked Immunosorbent Assay (ELISA) Three of the transcript variantsJAK1 encodes a membrane protein that is a member of a class of protein tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase related domain immediately N terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon alpha beta and interferon gamma signal transduction. Alternative splicing results in multiple transcript