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PKR Polyclonal Antibody, 20ul[BT-AP07245] Gene Editing Alternative splicing results in multiple

SKU: 79183487932

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PKR Polyclonal Antibody, 20ul[BT-AP07245] Gene Editing Alternative splicing results in multipleEukaryotic translation initiation factor 2 alpha kinase 2 encoded by EIF2AK2 is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of eukaryotic translation initiation factor 2 alpha kinase 2 can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. Eukaryotic translation initiation factor 2 alpha kinase 2 encoded by EIF2AK2 is also activated by

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Description

Alternative splicing results in multiple variants

Overexpression of PBK has been implicated in tumorigenesis

The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase

and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR)

have been identified for YWHAB

PKR Polyclonal Antibody, 20ul[BT-AP07245] Gene Editing Alternative splicing results in multipleEukaryotic translation initiation factor 2 alpha kinase 2 encoded by EIF2AK2 is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of eukaryotic translation initiation factor 2 alpha kinase 2 can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. Eukaryotic translation initiation factor 2 alpha kinase 2 encoded by EIF2AK2 is also activated by

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