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JAM-B Polyclonal Antibody, 50ul Proteases NFAT proteins are activated by

SKU: 78697071760

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JAM-B Polyclonal Antibody, 50ul Proteases NFAT proteins are activated byJAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. Junctional adhesion molecule B encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript

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Description

NFAT proteins are activated by the calmodulin-dependent phosphatase| calcineurin

forms the DNA binding domain of the polymerase

Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome

The encoded protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell

May be a tumor suppressor in brain cancers

JAM-B Polyclonal Antibody, 50ul Proteases NFAT proteins are activated byJAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. Junctional adhesion molecule B encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript

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