FGF-BP2 Polyclonal Antibody, 50ul Lysosome von Hippel-Lindau syndrome

von Hippel-Lindau syndrome

May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1

In a conventional activation pathway| I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators| subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus

Allelic variants in this gene have been associated with Dyggve-Melchior-Clausen syndrome and Smith-McCort dysplasia 2

The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity

FGF-BP2 Polyclonal Antibody, 50ul Lysosome von Hippel-Lindau syndromeFGFBP2 (fibroblast growth factor binding protein 2) encodes a member of the fibroblast growth factor binding protein family. The encoded protein is a serum protein that is selectively secreted by cytotoxic lymphocytes and may be involved in cytotoxic lymphocyte mediated immunity. An increase in the amount of gene product may be associated with atopic asthma and mild extrinsic asthma.