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MDM2 Polyclonal Antibody, 20ul[BT-AP05300] Molecular Sciences The encoded protein may be

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MDM2 Polyclonal Antibody, 20ul[BT-AP05300] Molecular Sciences The encoded protein may beMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation

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Easy to disassemble for maintenance

The encoded protein is a component of the multisubunit transport protein particle (TRAPP) complex

Cells directly thawed from liquid nitrogen or passaged from 2D culture vessels can be immediately mixed with the hydrogel solution for static suspension cultures

MDM2 Polyclonal Antibody, 20ul[BT-AP05300] Molecular Sciences The encoded protein may beMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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