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ATBF1 Polyclonal Antibody, 50ul Serum MED21 (mediator complex subunit 21)

SKU: 78308628929

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ATBF1 Polyclonal Antibody, 50ul Serum MED21 (mediator complex subunit 21)ZFHX3 encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha fetoprotein gene by binding to an AT rich enhancer motif. The protein has also been shown to negatively regulate c Myb, and transactivate the cell cycle inhibitor cyclin dependent kinase inhibitor 1A (also known as p21CIP1). ZFHX3 is reported to function as a

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Description

MED21 (mediator complex subunit 21) encodes a member of the mediator complex subunit 21 family

Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma

in the SIK/TORC signaling pathway

There are a variety of diseases associated with defects in chromosome 18-localized genes

leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF

ATBF1 Polyclonal Antibody, 50ul Serum MED21 (mediator complex subunit 21)ZFHX3 encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha fetoprotein gene by binding to an AT rich enhancer motif. The protein has also been shown to negatively regulate c Myb, and transactivate the cell cycle inhibitor cyclin dependent kinase inhibitor 1A (also known as p21CIP1). ZFHX3 is reported to function as a

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