Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0952] Dry Bath Several transcript variants encoding different

Several transcript variants encoding different isoforms have been found for CFLAR

It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes

Production of the surrogate light chain begins at the stage of pro-B cells

Mutations in CASP10 are associated with type IIA autoimmune lymphoproliferative syndrome

Splicing factor 3b

Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0952] Dry Bath Several transcript variants encoding differentThis gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG translation initiation