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TP53INP2 Polyclonal Antibody, 20ul[BT-AP09143] Pipette Controller The zinc finger protein 280A

SKU: 77989518402

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TP53INP2 Polyclonal Antibody, 20ul[BT-AP09143] Pipette Controller The zinc finger protein 280AThe protein encoded by TP53INP2 (tumor protein p53 inducible nuclear protein 2) promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1 RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes.

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Description

The zinc finger protein 280A contains 4 C2H2-type zinc fingers

These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain

interacting with nuclear transcription factor Y to activate UPR target genes

Mutations in this gene are a cause of hypomyelinating leukodystrophy

Maximum RCF up to 25

TP53INP2 Polyclonal Antibody, 20ul[BT-AP09143] Pipette Controller The zinc finger protein 280AThe protein encoded by TP53INP2 (tumor protein p53 inducible nuclear protein 2) promotes autophagy and is essential for proper autophagosome formation and processing. In addition, the encoded protein can enhance rDNA transcription by helping in the assembly of the POLR1 RNA polymerase I preinitiation complex. Finally, this protein serves as a transcriptional activator for some genes.

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