Phospho-B23 (T234) Polyclonal Antibody, 20ul Transporters It functions as a transcription

It functions as a transcription factor

it contains a conserved lysine residue in the seventh transmembrane domain

and insufficient production of the gene may disrupt normal embryonic development

Several alternatively spliced transcript variants encoding four distinct isoforms have been reported

G1/S-phase cyclin E-cdk2

Phospho-B23 (T234) Polyclonal Antibody, 20ul Transporters It functions as a transcriptionNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.