NADL2 Polyclonal Antibody, 50ul Buffers & Solutions Chloride intracellular channel 4 (CLIC4)

Chloride intracellular channel 4 (CLIC4) protein

|pharmaceutical:A constitutively active FOXO4 mutant where phosphorylation sites Thr-32| Ser-187 and Ser-262 have been mutated to alanine may have therapeutic potential in ERBB2/HER2-overexpressing cancers as it inhibits ERBB2-mediated cell survival| transformation and tumorigenicity

and maps to human chromosome 10q26

Some transcripts are predicted to be capable of translation reinitiation at a downstream AUG

This gene encodes a tumor suppressor related to the ADP-ribosylation factor (ARF) family of proteins

NADL2 Polyclonal Antibody, 50ul Buffers & Solutions Chloride intracellular channel 4 (CLIC4)Although related to the peptidase M28 family, it is probably inactive as an hydrolase due to lack of the conserved zinc binding and active sites.,May be catalytically inactive.,miscellaneous: The gene maps to 3q26. 31, a region associated with Cornelia de Lange syndrome. However, PubMed: 15168106 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome.,sequence Contaminating sequence at the C