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PITSLRE Polyclonal Antibody, 50ul Adeno-associated Virus Packaging belongs to the CDC50/LEM3 family

SKU: 76462339210

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DKK162.00 DKK199.00

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PITSLRE Polyclonal Antibody, 50ul Adeno-associated Virus Packaging belongs to the CDC50/LEM3 familyCDK11B encodes a member of the serine threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, CDK11B shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. Cyclin dependent kinase 11B encoded by CDK11B can be cleaved by caspases and may play a role in cell apoptosis. Alternative

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Description

belongs to the CDC50/LEM3 family

this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription

Translation of this protein is initiated at a non-AUG (AUA) start codon

The encoded protein (transcription factor AP-2 gamma) can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation

Mutations in TRHR have been associated with generalized thyrotropin-releasing hormone resistance

PITSLRE Polyclonal Antibody, 50ul Adeno-associated Virus Packaging belongs to the CDC50/LEM3 familyCDK11B encodes a member of the serine threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, CDK11B shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. Cyclin dependent kinase 11B encoded by CDK11B can be cleaved by caspases and may play a role in cell apoptosis. Alternative

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