JMJD2A Monoclonal Antibody, 100ul Recombinant Ab Production Binds to CCR4

Binds to CCR4

cytoplasmic dynein

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner

Fusion of ATF1 and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma

It has also been implicated in the pathogenesis of small cell lung cancer

JMJD2A Monoclonal Antibody, 100ul Recombinant Ab Production Binds to CCR4This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD type zinc fingers. This nuclear protein functions as a trimethylation specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.