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MASTL Polyclonal Antibody, 100ul Cell fragmentation and collection The signal sequence receptor (SSR)

SKU: 76150229372

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MASTL Polyclonal Antibody, 100ul Cell fragmentation and collection The signal sequence receptor (SSR)MASTL (microtubule associated serine threonine kinase like) encodes a microtubule associated serine threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia 2. Alternatively spliced transcript variants have been described for this locus.

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Description

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane

BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein

It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site

CHP2 was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520

and is found in either a latent form composed of a mature peptide homodimer

MASTL Polyclonal Antibody, 100ul Cell fragmentation and collection The signal sequence receptor (SSR)MASTL (microtubule associated serine threonine kinase like) encodes a microtubule associated serine threonine kinase. Mutations at this locus have been associated with autosomal dominant thrombocytopenia, also known as thrombocytopenia 2. Alternatively spliced transcript variants have been described for this locus.

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