XPA Polyclonal Antibody, 50ul Organelle Studies This protein induces apoptosis in

This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway

Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity

An additional variant encoding a different isoform has also been found for this gene

which hydrolyzes triglycerides and thus provides free fatty acids for cells

which is considered crucial to nuclear body interactions

XPA Polyclonal Antibody, 50ul Organelle Studies This protein induces apoptosis inXPA encodes a zinc finger protein involved in DNA excision repair. The DNA repair protein complementing XP A cells is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.