CALCOCO2 Rabbit Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) Transcription factor required for TBX21/T-bet-dependent

Transcription factor required for TBX21/T-bet-dependent maturation of Th1 cells as well as maintenance of Th1-specific gene expression

This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias

GBA3 is a polymorphic pseudogene

May also reduce the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites)

and degradation of macromolecules (Sardiello et al

CALCOCO2 Rabbit Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) Transcription factor required for TBX21/T-bet-dependentThis gene encodes a coiled coil domain containing protein. The encoded protein functions as a receptor for ubiquitin coated bacteria and plays an important role in innate immunity by mediating macroautophagy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.