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PGD Polyclonal Antibody, 50ul Vortex Mixer while defects in this gene

SKU: 75853430892

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PGD Polyclonal Antibody, 50ul Vortex Mixer while defects in this gene6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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Description

while defects in this gene are associated with multiple types of cancer

Death-associated protein 1 acts as a positive mediator of programmed cell death that is induced by interferon-gamma

The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride

The protein encoded by this gene is a nuclear protein that belongs to the family of Kruppel-like C2H2 zinc finger proteins

An important paralog of this gene is SERINC3

PGD Polyclonal Antibody, 50ul Vortex Mixer while defects in this gene6 phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6 phosphogluconate dehydrogenase and 6 phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

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