DEN1A Rabbit Polyclonal Antibody, 100ul Antibodies This gene family has multiple

This gene family has multiple members on both X and Y chromosomes| and all are expressed exclusively in male germ cells

increased susceptibility to rheumatoid arthritis

The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system

Alternatively spliced transcript variants encoding multiple isoforms have been observed for CASP7

The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase| which may mediate insulin signals to the actin cytoskeleton

DEN1A Rabbit Polyclonal Antibody, 100ul Antibodies This gene family has multipleClathrin (see MIM 118955) mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family such as DENND1A function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein 2 (AP2; see MIM 601024). Thus connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson 2010