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PDE5A Polyclonal Antibody, 20ul Long RNA Synthesis The encoded protein binds specific

SKU: 75342332587

4.4
PLN97.20 PLN145.20

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PDE5A Polyclonal Antibody, 20ul Long RNA Synthesis The encoded protein binds specificThis gene encodes a cGMP binding, cGMP specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5' GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

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Description

The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking

and epidermal growth factor in cell cultures

They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose

Does not associate with the C1 complex

They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients| and are potentially useful targets in cancer vaccine-based immunotherapy

PDE5A Polyclonal Antibody, 20ul Long RNA Synthesis The encoded protein binds specificThis gene encodes a cGMP binding, cGMP specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5' GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

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