Mouse Erythropoietin Receptor, EPOR ELISA Kit, 96T Recombinant Protein The rank order of potency

The rank order of potency for agonists of this receptor is propionate = pentanoate = butyrate > acetate > formate

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• Adjustable acceleration/deceleration at 9 levels allows gentle braking at low speed for better separation

Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3 (PubMed: 21737454

also involved in microtubule bundling and stabilization of existing microtubules

Mouse Erythropoietin Receptor, EPOR ELISA Kit, 96T Recombinant Protein The rank order of potencyReceptor for erythropoietin. Mediates erythropoietin induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2 STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.