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HXK I Polyclonal Antibody, 100ul Molecular Sciences The protein contains a series

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HXK I Polyclonal Antibody, 100ul Molecular Sciences The protein contains a seriesHexokinases phosphorylate glucose to produce glucose 6 phosphate, the first step in most glucose metabolism pathways. HK1 encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in HK1 have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue specific.

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Description

The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus

PKC family members also serve as major receptors for phorbol esters

the glomerular epithelial cells of the kidney

This gene encodes a single-pass membrane protein| which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily

or in an active form consisting solely of the mature peptide homodimer

HXK I Polyclonal Antibody, 100ul Molecular Sciences The protein contains a seriesHexokinases phosphorylate glucose to produce glucose 6 phosphate, the first step in most glucose metabolism pathways. HK1 encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in HK1 have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue specific.

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