SEP10 Polyclonal Antibody, 50ul Deep Well Plates Family members encode type II

Family members encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose

It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases

It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways

The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42

The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety

SEP10 Polyclonal Antibody, 50ul Deep Well Plates Family members encode type IIThis gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP binding and GTPase activity. A pseudogene for this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants.