Tyk 2(Phospho Tyr292) Rabbit Polyclonal Antibody, 50ul[BT-AP05347] Protein Post-translational Modification where it mediates both the

where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors

This protein associates with the embryonic ectoderm development protein| the VAV1 oncoprotein| and the X-linked nuclear protein

ubiquitination targets the protein for rapid degradation via the ubiquitin system

Among its related pathways are Oocyte meiosis and Mitotic Roles of Polo Like Kinases

including the products of tumor suppressor genes and dominant protooncogenes

Tyk 2(Phospho Tyr292) Rabbit Polyclonal Antibody, 50ul[BT-AP05347] Protein Post-translational Modification where it mediates both theThis gene encodes a member of the tyrosine kinase and more specifically the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such it may play a role in anti viral immunity. A mutation in this gene has been