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SLC4A8/10 Polyclonal Antibody, 50ul In vitro Assessment Recombination-associated motifs and translin-binding sites

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SLC4A8/10 Polyclonal Antibody, 50ul In vitro Assessment Recombination-associated motifs and translin-binding sitesSLC4A10 (solute carrier family 4 member 10) belongs to a small family of sodium coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by SLC4A10 was initially identified as a sodium driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium bicarbonate cotransport

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Description

Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations

Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3

Replication factor C

This gene is located in the cystatin locus and encodes a secreted protein that may play a role in hematopoietic differentiation or inflammation

Mutations of this class mu gene have been linked with a slight increase in a number of cancers| likely due to exposure with environmental toxins

SLC4A8/10 Polyclonal Antibody, 50ul In vitro Assessment Recombination-associated motifs and translin-binding sitesSLC4A10 (solute carrier family 4 member 10) belongs to a small family of sodium coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by SLC4A10 was initially identified as a sodium driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium bicarbonate cotransport

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