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Seprase Polyclonal Antibody, 20ul Human Genome Knockout Libraries highly expressed in brain

SKU: 74570994309

4.0
PLN97.20 PLN134.20

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Seprase Polyclonal Antibody, 20ul Human Genome Knockout Libraries highly expressed in brainThe fibroblast activation protein alpha encoded by FAP is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. Seprase is thought to be involved in the control of fibroblast growth or epithelial mesenchymal interactions during development, tissue

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Description

highly expressed in brain

and especially for cap-dependent translation of vesicular stomatitis virus mRNAs

Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms

An important paralog of this gene is WBSCR16

Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome

Seprase Polyclonal Antibody, 20ul Human Genome Knockout Libraries highly expressed in brainThe fibroblast activation protein alpha encoded by FAP is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. Seprase is thought to be involved in the control of fibroblast growth or epithelial mesenchymal interactions during development, tissue

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