Clock Monoclonal Antibody, 100ul Vortex Mixer The encoded protein recognizes an

The encoded protein recognizes an octamer sequence in the DNA of target genes

DLG4 and AIP1

Mutations in COL3A1 are associated with Ehlers-Danlos syndrome types IV

The encoded protein is also involved in MAP/ERK signaling pathway in specific cell types

pancreatic and leukemia

Clock Monoclonal Antibody, 100ul Vortex Mixer The encoded protein recognizes anThe protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix loop helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes.