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FAN Rabbit Polyclonal Antibody, 100ul Immune Cell Analysis subcellular location:Enriched in lipid rafts

SKU: 74294563723

4.8
DKK123.75 DKK171.75

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FAN Rabbit Polyclonal Antibody, 100ul Immune Cell Analysis subcellular location:Enriched in lipid raftsThis gene encodes a WD repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF mediated activation of neutral sphingomyelinase and may play a role in regulating TNF induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

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Description

subcellular location:Enriched in lipid rafts

|subunit:Binds to the receptor tyrosine kinases EPHA2| EPHA4| EPHA5| EPHA6 and EPHA7

This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation

the short isoform(14 kDa) has been shown to repress gamma-globin gene expression

these variants have not been fully described

FAN Rabbit Polyclonal Antibody, 100ul Immune Cell Analysis subcellular location:Enriched in lipid raftsThis gene encodes a WD repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF mediated activation of neutral sphingomyelinase and may play a role in regulating TNF induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.

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