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Raf-1 Polyclonal Antibody, 50ul[BT-AP13534] Cell Function Analysis It forms a 1-to-1 noncovalent

SKU: 74189883716

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Raf-1 Polyclonal Antibody, 50ul[BT-AP13534] Cell Function Analysis It forms a 1-to-1 noncovalentThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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Description

It forms a 1-to-1 noncovalent complex with glycoprotein Ib

Alternatively spliced transcript variants encoding different isoforms have been

Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth

Two transcript variants encoding different isoforms have been found for BCL7A

The protein has broad-spectrum antimicrobial activity against bacteria and fungi

Raf-1 Polyclonal Antibody, 50ul[BT-AP13534] Cell Function Analysis It forms a 1-to-1 noncovalentThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.

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