VCY1 Rabbit Polyclonal Antibody, 50ul Antibody Humanization Three functional domains exist in

Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain| a C-terminal self-association domain| and a membrane glycoprotein-binding domain

This encoded protein inhibits apoptosis induced by serum deprivation and menadione

Ser-59 phosphorylation decreases P311 stability

the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells)

A chromosomal aberration involving CRTC1 is found in mucoepidermoid carcinomas

VCY1 Rabbit Polyclonal Antibody, 50ul Antibody Humanization Three functional domains exist inThe protein encoded by this gene is a member of a family of human VCX Y genes. This gene family has multiple members on both X and Y chromosomes and all are expressed exclusively in male germ cells. Members of the VCX Y family share a high degree of sequence identity with the exception that a 30 bp unit is tandemly repeated in X linked members but occurs only once in Y linked members. VCX Y genes encode small and highly charged proteins of unknown