GRP78/Bip Monoclonal Antibody(8G3), 20ul Buffer Solutions This encoded protein (ATP binding

This encoded protein (ATP binding cassette subfamily A member 6) is a member of the ABC1 subfamily

but it has modest inhibitory effects on IL-4 production from Th2 T cells

shows frequent overexpression in prostate and breast carcinomas

It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs

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GRP78/Bip Monoclonal Antibody(8G3), 20ul Buffer Solutions This encoded protein (ATP bindingThe protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.