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CD329 Polyclonal Antibody, 50ul Cell Proliferation The protein has been implicated

SKU: 73225310593

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CD329 Polyclonal Antibody, 50ul Cell Proliferation The protein has been implicatedSialic acid binding immunoglobulin (Ig) like lectins, or SIGLECs (e. G. CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33 like subgroup of SIGLECs, which are localized to 19q13. q13. and have 2 conserved cytoplasmic tyrosine based motifs: an immunoreceptor tyrosine based inhibitory motif, or ITIM (see MIM 604964), and a motif

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Description

The protein has been implicated in the development of Alzheimer disease

and it thereby acts as a transcriptional repressor of Notch target genes

Variations in this gene are associated with susceptibility to coronary spasm

Considered to play a role in gender determination

In the Goodpasture syndrome

CD329 Polyclonal Antibody, 50ul Cell Proliferation The protein has been implicatedSialic acid binding immunoglobulin (Ig) like lectins, or SIGLECs (e. G. CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33 like subgroup of SIGLECs, which are localized to 19q13. q13. and have 2 conserved cytoplasmic tyrosine based motifs: an immunoreceptor tyrosine based inhibitory motif, or ITIM (see MIM 604964), and a motif

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