PLC gamma1(Phospho Tyr783) Polyclonal Antibody, 50ul Serological Pipets In vertebrates

In vertebrates

DYRK1A encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family

a putative transmembrane domain

which is predicted to span the membrane four times

and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals

PLC gamma1(Phospho Tyr783) Polyclonal Antibody, 50ul Serological Pipets In vertebratesThe protein encoded by this gene catalyzes the formation of inositol 1,4,5 trisphosphate and diacylglycerol from phosphatidylinositol 4,5 bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it