NDUB3 Polyclonal Antibody, 50ul Gene Editing |tissue specificity:Widely expressed| with highest

|tissue specificity:Widely expressed| with highest levels in spleen and lung

Six alternative splice variants have been identified

and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies

PTM:Phosphorylation of Thr-35 is required for activity

This gene is a member of the metallocarboxypeptidase gene family

NDUB3 Polyclonal Antibody, 50ul Gene Editing |tissue specificity:Widely expressed| with highestThis gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein.