MACC1 Polyclonal Antibody, 20ul Live Cell Imaging located on different chromosomes

located on different chromosomes

A pseudogene of CCNH is found on chromosome 4

It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin

Among its related pathways are Platelet activation

it is overexpressed in gynecological tumor samples

MACC1 Polyclonal Antibody, 20ul Live Cell Imaging located on different chromosomesMACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409) HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis free survival (Stein et al. 2009 [PubMed: 19098908]).