LYAG Rabbit Polyclonal Antibody, 50ul Sampling Tubes subcellular location:Localized in discrete vesicular

subcellular location:Localized in discrete vesicular and perinuclear structure

The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers

and it is part of a duplicated region of chromosome 1p36

The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains

as well as tumor suppressor protein BRCA1

LYAG Rabbit Polyclonal Antibody, 50ul Sampling Tubes subcellular location:Localized in discrete vesicularThis gene encodes lysosomal alpha glucosidase which is essential for the degradation of glycogen to glucose in lysosomes. The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme. Defects in this gene are the cause of glycogen storage disease II also known as Pompe's disease which is an autosomal recessive disorder with a broad clinical spectrum. Alternative splicing results in