EGFL5 Polyclonal Antibody, 50ul Peptide Modification signal transduction and transcription

signal transduction and transcription

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family

but unlike other family members

It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT

with substantial levels also detected in amygdala and thalamus

EGFL5 Polyclonal Antibody, 50ul Peptide Modification signal transduction and transcriptionMEGF9 (Multiple EGFlike domains protein 9; also EGFlike protein 5) is a 63 kDa (predicted) novel transmembrane glycoprotein that shares some homology to beta chains of laminin. It is expressed by hepatocytes, cerebellar Purkinje cells, Schwann cells, keratinocytes and intestinal epithelium. MEGF9 is suggested to participate in cell motility, and its absence correlates with tumor cell migration. Mature human MEGF9 is 572 amino acids (aa) in length. It