Ku-80 Polyclonal Antibody, 20ul[BT-AP04902] Recombinant Ab Production Histidine--tRNA ligase cytoplasmic encoded by

Histidine--tRNA ligase cytoplasmic encoded by HARS is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases

Mutations in this gene are a cause of Kostmann syndrome

which together with an alpha and a gamma subunit

Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107

The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase

Ku-80 Polyclonal Antibody, 20ul[BT-AP04902] Recombinant Ab Production Histidine--tRNA ligase cytoplasmic encoded byThe protein encoded by XRCC5 (X ray repair cross complementing 5) is the 80 kilodalton subunit of the Ku heterodimer protein which is also known as ATP dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA binding component of the DNA dependent protein kinase, and it functions together with the DNA ligase IV XRCC4 complex in the repair of DNA double strand break by non homologous end joining and the completion of V(D)J recombination