MDM2 Polyclonal Antibody, 50ul[BT-AP05300] Vacuum Aspirator The product of this gene

The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism

tissue specificity:In brain

gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS)

These enzymes modify nuclear proteins by poly-ADP-ribosylation

As a monomer

MDM2 Polyclonal Antibody, 50ul[BT-AP05300] Vacuum Aspirator The product of this geneMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript