p53R2 Polyclonal Antibody, 100ul Vessels The encoded protein is cadherin-like

The encoded protein is cadherin-like

The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function

Inhibits SIRT1 in a CHEK2 and PSEM3-dependent manner and inhibits the activity of CHEK2 in vitro (PubMed: 25361978)

Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains

This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside

p53R2 Polyclonal Antibody, 100ul Vessels The encoded protein is cadherin-likeRRM2B encodes the small subunit of a p53 inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in RRM2B have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia 5, and mitochondrial